Machanism of action (MoA)
ASD001 suppresses innate immune functions by activating CD11b on innate immune cells. ASD001 can help to restore intestinal barrier homeostasis during barrier breach by reverting innate immune cells to immune suppressive phenotypes and an increase in IL-10 production and decrease in TNF-a secretion. In addition, ASD001 can also suppress neutrophil extracellular traps formation, leading to a reduction in further tissue damage.
